Prostate Cancer by Donald J Tindall
//
Prostate cancer is the most frequently diagnosed non-cutaneous malignancy in men
and the second leading cause of male cancer-related mortality in the USA. The last
decade has seen unprecedented progress in the detection, prognosis, treatment, and
prevention of prostate cancer. These advances have been driven largely by an increased
understanding of the underlying biochemistry, molecular biology, and genetics of the
disease. New cell and animal models have been developed that recapitulate the natu-
ral progression of prostate cancer. New technologies have allowed scientists to view
in detail the genomic, proteomic, metabolomics, and other—omic universe of cancer
cells and tissues. This has resulted in a greater understanding of the pathophysiology
of the disease. The purpose of this book will be to provide an up-to-date review of the
biochemistry, molecular biology, and genetic changes in prostate cells that are the
driving forces in the initiation and progression of cancer. It will include an overview
by experts in the fi eld of cell–cell interactions, including stem cells, reactive stromal
cells, and membrane lipid rafts that are instrumental in the initiation and progression
of prostate cancer.
کتاب : سرطان پروستات ، نویسنده : دانالد تیندال
